The side effects of zinc sulfate include abdominal pain, vomiting, headache and feeling tired. Although normal doses of zinc sulfate during pregnancy and breastfeeding are safe, the safety of high doses are not known. Renal failure patients must be more careful when using this medicine. Zinc considers a main mineral for humans and other animals. The medical use of zinc sulfate has early started in the 17th century. It is on the WHO List of essential medicines, and it is the safest and most effective medicine in the healthcare system. It is over-the-counter medicine, and its wholesale price daily ranges from 0.01 to 18 $ in developing countries. In the UK, the cost of this medicine for 10 days is 4.32 £.