The side effects of this medicine include vomiting, joints pain, mood changes, physiological disorders and ringing in the ears. The safety of this medicine on pregnant women weren’t determined. In the cases of cyanide poisoning, sodium nitrate produces methemoglobinemia that removes cyanide from mitochondria. The sodium thiosulfate then connects to the cyanide to form a non-toxic thiocyanate.
Sodium thiosulphate is used as a treatment for cyanide poisoning and tinea versicolor. It is also used to reduce the side effects of Cisplatin. For cyanide poisoning, sodium thiosulphate is used often after sodium nitrite, and it is recommended in general to use sodium nitrite for only severe cases. It can be intravenously taken or put on the skin.